What Meds

Psychiatric Medications


Amphetamine and Dextroamphetamine Mixed Salts
Brand Name: Adderall, Adderall XR

Overview
Adderall contains amphetamine and dextroamphetamine, which are stimulants. This drug is used to:

An advantage of Adderall is that it is effective for most patients when taken once or twice a day. This makes it convenient for patients, parents and caregivers. Adderall may help some patients for whom other medications, such as Ritalin have not been effective. The effects of Adderall can be felt after a few doses. It may take additional time to achieve the full effect and this may require adjusting dosages. Most people can achieve maximum benefit in 3 to 4 weeks.

Why is this drug prescribed?
Adderall is FDA-approved used to treat Attention Deficit Disorder with Hyperactivity (ADHD) in children age 3 and up (immediate-release only), children and adolescents age 6-17 (extended-release only), and adults. It is prescribed for the following symptoms in children:

When these symptoms first appear, other factors should be considered, such as neurological signs, learning disability, abnormal EEG and central nervous system dysfunction.

Adderall is also FDA-approved to treat narcolepsy in children age 6 and up (immediate-release only) and adults (immediate-release only)

Amphetamines have been used since the 1960s to treat symptoms of ADHD. Adderall’s duration of action is around 6 hrs, while Adderall XR, the extended release formulation, has a duration of action of 10-12 hrs. Adderall XR is currently the most commonly prescribed medication for the treatment of ADHD in the US.

Warnings and Precautions
Amphetamines have a high potential for abuse. Administration of amphetamines for prolonged periods may lead to drug dependence. There is a danger of obtaining amphetamines for non-therapeutic use or distribution to others.

Clinical experience suggests that in psychotic children, amphetamines may exacerbate symptoms of behavior disturbance and thought disorder. Chronic administration of amphetamines may be associated with growth inhibition. Therefore, growth should be monitored during treatment.

The least amount feasible should be dispensed at one time, in order to minimize the possibility of over dosage.

Amphetamines may impair the ability of the patient to engage in potentially hazardous activities, such as operating machinery or vehicles.

For Nursing Mothers: Amphetamines are excreted in human milk. Mothers taking amphetamines should refrain from nursing.

Contraindications
Adderall should Not be used for people who have:

Adverse Reactions
Amphetamines may cause the following reactions:

Rarely:

There have been isolated reports of heart disease associated with chronic amphetamine use.

Interactions with Drugs and Other Substances
Drugs or substances that may interact with Adderall include:

Research Studies
Adderall XR has been shown in four published randomized, placebo-controlled studies (2 in children aged 6-12, one in adolescents, and one in adults) to have significant improvements in ADHD symptoms.

Sources

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